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1.
Cent European J Urol ; 76(3): 207-211, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38045776

RESUMO

Introduction: The aim of this study was to investigate the effect of nocturnal enuresis (NE) in childhood on the development and course of overactive bladder (OAB) in adulthood. Material and methods: Between January and September 2021, data from patients who visited the Urology Outpatient Clinic with OAB symptoms were collected. Patients with a history of diabetes mellitus, neurological diseases, bladder outlet obstruction, active urinary system infection, or previous medical treatment for OAB and those who did not agree to join the study were excluded. Patients with a diagnosis of NE in childhood were classified as group 1, and patients without a diagnosis of NE were classified as group 2. Demographic data were recorded. Frequency of incontinence, and the number of daytime voids and nocturia were evaluated according to a three-day voiding diary. In addition, the maximum urinary flow ratio (Qmax), bladder wall thickness, and postvoid residual volume were determined using uroflowmetry and pelvic ultrasound. Results: After applying the inclusion/exclusion criteria, the mean age of the study group of 103 patients, consisting of 34 women and 69 men, was 32.85 ±11.20 years (18-65), and the mean BMI of both groups was 26.62 ±3.34 (19.49-39.18). Sixty-five of 103 patients (63.1%) had a history of childhood NE diagnosis. Patients in the group with a history of NE were younger than those without a history of NE. Conclusions: The earlier onset and more intense course of OAB symptoms in patients diagnosed with NE in childhood suggests that NE may be a triggering factor in the aetiology of OAB.

2.
J Coll Physicians Surg Pak ; 32(5): 623-626, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35546699

RESUMO

OBJECTIVE: To evaluate the efficacy of retrograde intrarenal surgery (RIRS) and holmium laser lithotripsy in the treatment of symptomatic renal calyceal diverticular (CD) stones. STUDY DESIGN: A case series. PLACE AND DURATION OF STUDY: Department of Urology, Hisar Intercontinental Hospital, from 2008 and 2019. METHODOLOGY: Patients who underwent holmium laser lithotripsy with RIRS to manage symptomatic CD stones were evaluated retrospectively. Demographics, stone size, operation and hospital stay duration, the success of treatment and complications were noted. RESULT: Among the 30 treated patients, 13 patients were female and 17 were male. The mean age was 45.4 ± 11.9 (26-64), the stone diameter was 14.4 ± 4.1 mm, operation time was 70.47±35.7 (35-155) minutes, and mean length of hospital stay was 1.27±0.5 (1-3) days. In those patients who underwent RIRS, 26 (86.7%) were successfully treated while in 4 of 30 patients (13.3%) the procedure was not successful. Complications were observed in 10 (33.3%) patients. Clavien-I complications were demonstrated in 6 patients, Clavien III complications were demonstrated in 3 patients. One patient had urosepsis, 2 patients had ureteral laceration, and one patient with Clavien IV complication had perirenal hematoma. CONCLUSION: Laser lithotripsy therapy with RIRS is a safe and effective treatment for symptomatic calyceal diverticular stones and can be offered as the first-line treatment for calyceal diverticular stones. KEY WORDS: Calyceal diverticula, Stone disease, Flexible ureterorenoscopy, Holmium laser, RIRS.


Assuntos
Divertículo , Cálculos Renais , Litotripsia , Adulto , Divertículo/complicações , Divertículo/cirurgia , Feminino , Hólmio , Humanos , Cálculos Renais/complicações , Cálculos Renais/cirurgia , Litotripsia/efeitos adversos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
3.
Br J Radiol ; 95(1135): 20220229, 2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-35357892

RESUMO

OBJECTIVE: Several pre-operative parameters have been studied to estimate stone-free rate (SFR) following retrograde intrarenal surgery (RIRS) procedures. The objective of this study was to evaluate the effects of stone density on surgical outcomes of RIRS. METHODS: This retrospective study included 30 stone-free patients (Group SF) and 30 patients with residual fragments (Group RF). Patients' age and gender, laterality, non-contrast CT findings, including size and density of the kidney stones, infundibular pelvic angle (IPA), operational time, and post-operative pain were recorded and compared between the two groups. The stone density was measured by free hand region of interest (ROI) determination coincident with the stone borders and expressed as Hounsfield units (HUs). RESULTS: The rate of single stones was significantly higher in Group SF compared to Group RF (p < 0.001). The mean stone size was found as 11.93 ± 7.81 mm in Group SF and 16.27 ± 7.29 mm in Group RF with the difference being statistically significant (p < 0.001). The mean IPA was 53.87 degrees in Group SF and 50.33 degrees in Group RF. The mean density was measured as 748.17 ± 318.14 HU in Group SF and 945.90 ± 345.30 HU in Group RF. The mean stone density was statistically significantly higher in patients with residual fragments compared to the stone-free patients (p < 0.001). CONCLUSION: This study revealed that stone density as measured as HU affects the treatment outcomes with RIRS procedure and the mean density is significantly higher in patients with residual stone fragments. ADVANCES IN KNOWLEDGE: Studies about the effects of HUs on stone-free rate are limited in the literature. Stone density affects the treatment outcomes with RIRS procedure and the mean density is significantly higher in patients with residual stone fragments.


Assuntos
Cálculos Renais , Rim , Humanos , Rim/cirurgia , Cálculos Renais/diagnóstico por imagem , Cálculos Renais/cirurgia , Duração da Cirurgia , Estudos Retrospectivos , Resultado do Tratamento
4.
Urologia ; 89(1): 108-113, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33729060

RESUMO

OBJECTIVE: To objective of this study was to investigate poor scar appearance of the circumcision line and scar wrinkling caused by the sutures placed during the circumcision in primary school age circumcised children. METHODS: A total of 455 children aged between 6 and 9 years, circumcised by four different specialists in our hospital between 2009 and 2018 were evaluated. Circumcisions performed due to balanitis, phimosis, secondary phimosis, and paraphimosis were excluded from the study. Only routine religious circumcisions performed on request of the family were included in the study. Children underwent a second procedure and those receiving treatment after the circumcision due to infection were excluded from the study. About 363 patients included the study. Patients were evaluated according to the Fitzpatrick skin type classification, independent observer scale, Stony Brook Scar Evaluation Scale, and Dunn-Bonferroni test. RESULTS: No statistically significant difference was found between distributions of scar wrinkling levels in children according to the circumcision (p > 0.05). There was a statistically significant difference between age of circumcision according to scare wrinkling levels (p = 0.001). According to the Dunn-Bonferroni test; the circumcision age was found to be significantly lower in children with severe scar wrinkling compared to the children with no or mild scar wrinkling (p = 0.001; p = 0.011). CONCLUSION: The tense, short-interval sutures placed away from the wound margin during circumcision in order to control subcutaneous bleeding lead to scar wrinkling and a poor cosmetic appearance. Knowing the risk factors leading to scar wrinkling and taking appropriate measures will provide acceptable cosmetic outcomes after the circumcision.


Assuntos
Circuncisão Masculina , Fimose , Criança , Cicatriz/etiologia , Hemostasia , Humanos , Masculino , Fimose/etiologia , Fimose/cirurgia , Suturas , Resultado do Tratamento
5.
Dermatitis ; 32(6): 388-396, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34807531

RESUMO

BACKGROUND: Health care workers and hospital cleaning workers are at high risk regarding the development of occupational contact dermatitis (OCD). OBJECTIVES: To determine the prevalence and risk factors of OCD in hospital cleaning workers. METHODS: A questionnaire was conducted in 245 cleaning workers in our cross-sectional study. The 236 cleaning workers formed the study group. In workers who were prediagnosed with dermatitis, physical examination was performed in the Dermatology Outpatient Clinic, and when necessary, patch test, skin biopsy, and investigation for total immunoglobulin E were conducted. Patients with definite contact dermatitis were diagnosed as having OCD by using the Mathias criteria. RESULTS: The prevalence rate of OCD was 21.6% and was significantly higher in female workers (26.4%) when compared with male workers (11.0%). Female sex; low educational level; cleaning the external surfaces of the medical equipment, monitors, and accessories; and mixing the cleaning products and use them while performing cleaning activities were determined as the independent risk factors for OCD. CONCLUSIONS: Occupational contact dermatitis was present at a high rate in hospital cleaning workers. The risk factors should be taken into consideration for prevention of OCD and improvement of the health status of hospital cleaning workers.


Assuntos
Dermatite Ocupacional/epidemiologia , Detergentes/efeitos adversos , Zeladoria/estatística & dados numéricos , Exposição Ocupacional/efeitos adversos , Estudos Transversais , Dermatite Ocupacional/diagnóstico , Dermatite Ocupacional/etiologia , Feminino , Hospitais , Humanos , Irritantes/efeitos adversos , Masculino , Testes do Emplastro/estatística & dados numéricos , Prevalência , Turquia
6.
Sex Med ; 9(2): 100313, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33529814

RESUMO

INTRODUCTION: Platelet-rich plasma (PRP) is useful in the treatment of different conditions and diseases as it contains concentrated levels of many growth factors. AIM: The aim of this study was to investigate the effectiveness of autologous PRP application in the treatment of erectile dysfunction (ED) in patients with metabolic syndrome. METHODS: In this prospective study conducted in June 2019, 31 patients with ED were included. The International Index of Erectile Function-Erectile Function domain (IIEF-EF) questionnaires were used to evaluate erectile function (EF). After administering the intracavernous autologous PRP 3 times with an interval of 15 days, IIEF-EFs were evaluated 1, 3, and 6 months later. MAIN OUTCOME MEASURE: IIEF in the 1st, 3rd, and 6th months and adverse events. RESULTS: While the mean IIEF-EF was 18 before the application, the mean IIEF-EF was 20 in the first, third, and sixth months after the procedure (P < .001). However, even though IIEF-EF values increased numerically, median value remained within the mild-moderate classification (scores between 17 and 21). Postprocedure sexual satisfaction scores were significantly higher than preprocedure values (8 vs 6, respectively; P = .002). In the first follow-up of a patient after the 3rd injection, a 4-mm diameter fibrotic plaque was observed on the ventral side in the middle of the penis shaft. CONCLUSION: In conclusion, our findings suggest that larger studies as well as placebo-controlled studies are needed to add PRP to the treatment protocol in ED. T Tas,Çakiroglu, E Arda, et al. Early Clinical Results of the Tolerability, Safety, and Efficacy of Autologous Platelet-Rich Plasma Administration in Erectile Dysfunction. Sex Med 2021;9:100313.

7.
Turk J Urol ; 46(6): 455-459, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32966206

RESUMO

OBJECTIVE: This study aimed to evaluate the opinions of urologists from different countries about uro-oncology education, fellowship programs, and approaches to different urological malignancies at different stages using a questionnaire. MATERIAL AND METHODS: A total of 207 urologists from 22 countries were sent a questionnaire containing 18 items by email. The questions were related to urologic oncology training provided during residency, acceptance of uro-oncology as a sub-branch, the necessity of certification for treatment and follow-up, fellowship program preferences, adequateness of the programs, and approach differences to the different stages of urological malignancies among the urologists from different countries. RESULTS: In total, 111 (53.62%) urologists who completed the questionnaire were enrolled in the study, and 40.54% of the urologists reported that the uro-oncology training during the residency period was not sufficient. Furthermore, 79.27% of the urologists reported opinions about acceptance of uro-oncology as a sub-branch. The ratio of urologists who undertake the treatment of patients with muscle-invasive bladder cancer (radical surgery and urinary diversion) and prostate cancer (radical prostatectomy, definitive radiation therapy, experimental local treatment, and hormonal therapy) is 27.92% and 37.83%, respectively. The urologists reported that they perform nephron-sparing surgery (NSS), radical nephrectomy (RN), and laparoscopic NSS/RN treatments in patients with localized renal cancer at the rates of 61.26%, 47.74%, and 25.22%, respectively. CONCLUSION: Uro-oncology training during the residency period seems to be inadequate in most of the countries, and a high number of the urologists tend to avoid high-volume operations and systemic treatments of uro-oncologic malignancies.

8.
Obes Surg ; 30(12): 4768-4773, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32725592

RESUMO

PURPOSE: Majority of men with type 2 diabetes mellitus (T2DM) have been reported to experience erectile dysfunction (ED) in a lifetime. The aim of our study was to prospectively evaluate the postoperative condition of ED and premature ejaculation (PE) in men who underwent metabolic surgery for the treatment of T2DM. MATERIALS AND METHODS: A total of 36 sexually active male individuals with T2DM who were applied for metabolic surgery were given two different questionnaire forms prior to and 6 months after the surgery. Patients filled the International Index of Erectile Function (IIEF) and the Premature Ejaculation Profile (PEP) questionnaires before and 6 months after the surgery. The BMI, fasting blood glucose (FBG), and glycated hemoglobin (HbA1c) concentrations were also measured prior to the surgery and on follow-up points of postoperative first, third, and sixth months. RESULTS: Erectile function (EF) and overall satisfaction domains of the IIEF questionnaire increased significantly after the surgery in the patient groups irrespective of the previous ED severity (p < 0.001). There were significant improvements of the PEP interpersonal difficulty related to ejaculation score and HbA1c levels in the severe/moderate EF group and IIEF EF, PEP interpersonal difficulty related to ejaculation domains, and HbA1c levels of mild to moderate/mild/no ED group after the metabolic surgery. CONCLUSION: Metabolic surgery could improve erectile and ejaculatory function scores of obese patients with T2DM.


Assuntos
Cirurgia Bariátrica , Diabetes Mellitus Tipo 2 , Disfunção Erétil , Obesidade Mórbida , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/cirurgia , Ejaculação , Disfunção Erétil/etiologia , Humanos , Masculino , Obesidade , Obesidade Mórbida/cirurgia , Projetos Piloto , Inquéritos e Questionários
9.
Ther Adv Urol ; 11: 1756287219882598, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31662793

RESUMO

OBJECTIVE: The objective of this study was to evaluate the reliability of thermocautery-assisted circumcision performed voluntarily in patients of poor countries. MATERIAL AND METHODS: Between 2016 and 2019, 32,000 children aged 7 days to 17 years were circumcised in multiple countries. The patients' urological examinations were done before the administration of local anaesthesia. Patients revealed to have undescended testicle, inguinal hernia, hypospadias, varicocele, penile rotation anomaly, epispadias and infection were not circumcised. All procedures were performed under local anaesthesia by using thermocautery. Afterwards, mucosa and skin were sutured using absorbable suture and the circumcised penis was dressed. Patients were instructed to remove the dressing after 3 days. RESULTS: Bleeding, requiring surgical intervention and drug reactions were not observed. The most observed complication was mucosal oedema, which occurred in approximately one-quarter of patients (26%, 8320/32,000) and continued for 3-5 days after the surgery. The most serious complication was a trapped penis, which occurred in 25 patients (0.078%). In six (0.018%) cases, meatal stenosis developed. Wound infection developed in only 10 (0.03%) cases, through the formation of an aseptic environment. Penile adhesion was seen in 35 cases (0.1%) and improved with anti-inflammatory treatment without any surgical intervention. CONCLUSION: Thermocautery-assisted circumcision can be used as an effective, safe and useful technique with few complications and rapid healing rates.

10.
Urologia ; 86(4): 202-206, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31116682

RESUMO

BACKGROUND: The purpose of this study is to investigate the representativeness of the conventional laparoscopic standard box trainers in terms of real-life circumstances in transperitoneal laparoscopical interventions of the upper tract, using questionnaire inquiries with experienced surgeons. MATERIALS AND METHODS: The study was conducted with 44 laparoscopists, whose level of renal surgery experience was either high (primary surgeon in >100 cases), moderate (primary surgeon in >50 cases) or basic (primary surgeon in >20 cases). We used the box widely preferred in international training courses, which consists of a 10-mm 30° laparoscope, real endoscopic instruments, light source, monitor and chicken bone materials. Participants were asked whether they represent real-life situations while performing tasks by means of standard box trainers. RESULTS: The medians of 'restrained body posture of the surgeon', 'position of monitor', 'trocars entry slots', 'tissue distance and region' and 'limited field of movement and restricted working space' were analysed on their difference from the ideal value. All the variables were shown to be significantly different from the ideal value of 5 (p < 0.001). These results suggest that experienced surgeons in our study did not find the box simulation conditions similar to real surgery conditions. CONCLUSION: Conventional laparoscopic trainer box, which is currently being used, is far from representing for the real situation in transperitoneal laparoscopical interventions of the upper tract.


Assuntos
Laparoscopia/educação , Laparoscopia/métodos , Treinamento por Simulação/métodos , Trato Gastrointestinal Superior/cirurgia , Modelos Anatômicos , Peritônio
11.
Afr J Paediatr Surg ; 15(3): 131-134, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-32769363

RESUMO

PURPOSE: The purpose of this study was to compare the rates of success, relapse, and compliance to treatment in patients undergoing alarm therapy or receiving desmopressin for primary monosymptomatic nocturnal enuresis (PMNE). MATERIALS AND METHODS: This retrospective study was performed by reviewing the medical files of patients undergoing alarm therapy (Group 1) or receiving desmopressin (Group 2) for PMNE, between January 2010 and July 2014. Patients undergoing treatment in the 3rd and 6th month as well as 1st year follow-up data were analyzed. Two groups were compared with regard to treatment success, relapse rate, and compliance to treatment. RESULTS: Group 1 included 64 and Group 2 included 70 children. Relapse rates at the 3rd month, 6th month, and 1st year were 67.2%, 71.9%, and 17.0% for Group 1 and 74.3%, 80.0%, and 21.4% for Group 2, respectively. There was no statistically significant difference between relapse rates at any point of follow-up. CONCLUSIONS: Alarm therapy and desmopressin have the same success rate and relapse rates for PMNE. Compliance with alarm therapy is higher and we recommend it as the first-line treatment. On the other hand, desmopressin has low side effects and can also be used.

12.
Mediterr J Hematol Infect Dis ; 8(1): e2016059, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27872739

RESUMO

OBJECTIVE: The aim of this study is to describe the epidemiological and clinical aspects of patients who applied to the Bursa Nilufer Tuberculosis Dispensary by investigating the trends in epidemics over three decades. METHOD: In this retrospective observational study, the records of all tuberculosis cases (1630 patients) treated in the last 30 years (1985-2014) at the Bursa Nilufer Tuberculosis Dispensary were examined and statistically analyzed. RESULTS: Males comprised 65.2% of the patients. The ages of the patients ranged from 1 to 87 years, and the mean age was 37.4 (95% CI: 36.6-38.2). Among the cases, 86.7% were new infections and 74.1% were pulmonary tuberculosis. In the last decade, the education level, the percentage of patients who had received a BCG vaccination, the proportion of women and active employees among them increased (p<0.05), while it decreased among men (p<0.05). Clinical symptoms accompanying TB such as weakness, anorexia, weight loss, and cough, decreased to a statistically significant degree (p<0.05). In the last decade, the mortality rate was 3.6% and increased compared with previous decades (p<0.05). Mortality was higher among patients who were elderly, male, did not have a BCG scar or had a chronic disease (p<0.05). CONCLUSION: This study adds information about the change of TB epidemics in Turkey in the last 30 years. Further studies are needed to determine the risk factors associated with tuberculosis mortality and to evaluate the effectiveness control programs of this disease.

13.
Urology ; 97: 227-231, 2016 11.
Artigo em Inglês | MEDLINE | ID: mdl-27476153

RESUMO

OBJECTIVE: To determine the positive subdomain numbers and distribution of the UPOINT classification in chronic prostatitis and to compare the erectile dysfunction (ED) pattern. MATERIALS AND METHODS: From 2008 to 2013, 839 patients with symptomatic chronic prostatitis or chronic pelvic pain syndrome were included in this study. The correlation between UPOINT domains and National Institutes of Health chronic prostatitis symptom index (NIH-CPSI) total score, subscores, and the 5-item International Index of Erectile Function scores were evaluated retrospectively. RESULTS: The mean patient age was calculated as 37.7 ± 7.4 (range 21-65). The average total NIH-CPSI score was determined as 9.07 (range 1-40) and the average positive UPOINT subdomain number was determined as 2.87 ± 0.32 (range 1-6). Subdomain patient numbers and rates were calculated as 529 urinary (63%), 462 psychosocial (55%), 382 organ specific (45%), 290 infection (34%), 288 neurological or systemic (34%), and 418 tenderness (skeletal muscle) (50%), respectively. It was determined that ED, determining the subdomain of sexual dysfunction in patients, was positive in a total of 326 (39.9%) patients, with 220 patients having mild (26.2%), 76 mild to moderate (9.1%), 19 moderate (2.3%), and 5 with severe (0.6%) ED. A statistically significant correlation was not determined between the 5-item International Index of Erectile Function score and UPOINT subdomain number and NIH-CPSI score. CONCLUSION: It has been determined that although there is a strong and significant correlation between UPOINT classification and NIH-CPSI score in Turkish patients with chronic prostatitis or chronic pelvic pain syndrome, the inclusion of ED as an independent subdomain to the UPOINT classification is not statistically significant.


Assuntos
Dor Pélvica/classificação , Prostatite/classificação , Inquéritos e Questionários , Adulto , Idoso , Doença Crônica , Disfunção Erétil/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Dor Pélvica/complicações , Fenótipo , Prostatite/complicações , Estudos Retrospectivos , Índice de Gravidade de Doença , Síndrome , Turquia , Adulto Jovem
14.
Arch Ital Urol Androl ; 88(4): 262-265, 2016 Dec 30.
Artigo em Inglês | MEDLINE | ID: mdl-28073189

RESUMO

AIM: To determine the relationship between inguinal hernia (and inguinal hernia subtypes) and low urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH), that could be more common than we think. METHOD: The study was designed retrospectively and was done in accordance with the principles of the Declaration of Helsinki, including 100 patients aged > 50 years that were divided into 2 groups: patients with BPH (BPH group) and patients with BPH and inguinal hernia (BPH-IH group 2). In addition, the BPH-IH group was subdivided according to 2 inguinal hernia subtypes; patients of BPH-IH subgroup A had direct inguinal hernia (n = 25) and those of BPH-IH subgroup B had indirect inguinal hernia (n = 25). RESULTS: There was no statistical relationship and difference in rates between IPSS scores in both groups (p = 0.659) and there wasn't a significant correlation between IPSS symptom severity and type of hernia, based on chi square analysis (p = 0.104) Conclusion: We were not able to prove our hypothesis that patients with inguinal hernia and BPH would have higher IPSS scores because of voiding dysfunction.


Assuntos
Hérnia Inguinal/etiologia , Sintomas do Trato Urinário Inferior/etiologia , Hiperplasia Prostática/complicações , Idoso , Idoso de 80 Anos ou mais , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
15.
Arch Ital Urol Androl ; 87(3): 198-203, 2015 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-26428640

RESUMO

OBJECTIVE: The aim of this study was to enlighten both the testicular histology and the genetic aspects of the apoptotic process. Thus an experimental study was designed with a model of unilateral vasectomy. METHODS: Twenty-two adult male rats were used and 4 main groups were formed. The first (A), the second (B), the third (C), and the fourth group (D) consisted of 4, 4, 4 and 10 rats respectively. Rats in group A had sham operation while rats in other groups (B, C, D) underwent left vasectomy operation including binding of ductus deferens with a 3/0 silk and cutting a minimum of 1 cm part while preserving the vascular structure under 9x magnification. Rats undergoing unilateral vasectomy were sacrificed at the 1(st), 2(nd) and 8(th) weeks and their testicular structure and proapoptotic gene proteins were compared with that of the control group undergoing sham operation. RESULTS: We found that vasectomy gradually caused destruction and both ipsilateral and contralateral testicles were affected showing initial apoptosis. CONCLUSION: The procedure causes destruction in the testicular structure by causing bilateral intratubular germ cell necrosis, unilateral obstruction, increase in the tubular pressure and processes that are aggravated by some probable autoimmune reactions.


Assuntos
Apoptose , Testículo/patologia , Testículo/fisiopatologia , Vasectomia/efeitos adversos , Animais , Apoptose/genética , Modelos Animais de Doenças , Humanos , Masculino , Estresse Oxidativo , Ratos , Ratos Sprague-Dawley , Túbulos Seminíferos/patologia , Túbulos Seminíferos/fisiopatologia , Espermatozoides/patologia , Testículo/metabolismo , Vasectomia/métodos
16.
Arch Ital Urol Androl ; 87(1): 38-40, 2015 Mar 31.
Artigo em Inglês | MEDLINE | ID: mdl-25847895

RESUMO

OBJECTIVE: To compare the outcomes of shock wave lithotripsy (SWL) combined with inclined position and SWL alone in patients with lower pole calyx stones. METHODS: Seven hundred forty patients who underwent SWL treatment for lower pole renal stones with a total diameter of 2 cm or less were prospectively randomized into two groups. They were comparable in terms of age, sex, and stone diameters. Patients with lower calyceal stones (4-20 mm) were randomized to SWL (368 patients) or SWL with simultaneous inclination (372 patients) with 30o head down Trendelenburg position). Shock wave and session numbers were standardized according to stone size. Additional standardized shock waves were given to patients with stone fragments determined by kidney urinary bladder film and ultrasound at weeks 1, 4, 10. RESULTS: The overall stone free rate (SFR) was 73% (268/368) in patients with SWL alone and 81% (300/372) in SWL with inclination at the end of 12th week (p = 0.015). No significant adverse events were noted in both treatment groups. CONCLUSION: Simultaneous inclination of patients during SWL session increase SFR in lower caliceal stones significantly compared to SWL treatment alone.


Assuntos
Decúbito Inclinado com Rebaixamento da Cabeça , Cálculos Renais/terapia , Cálices Renais , Litotripsia a Laser , Adulto , Feminino , Seguimentos , Humanos , Cálculos Renais/diagnóstico , Litotripsia a Laser/métodos , Masculino , Estudos Prospectivos , Resultado do Tratamento
17.
Int J Surg Case Rep ; 6C: 48-50, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25524301

RESUMO

INTRODUCTION: Although lipomas are the most common mesenchymal tumors of the human body, primary intrarenal lipomas are quite rare. In this report we present a case of benign mesenchymal tumor with lipomatous and myxoid components. PRESENTATION OF CASE: A sixty one years old male patient was admitted to our outpatient clinic for a general control since he had a right radical nephrectomy operation due to renal cell carcinoma (RCC) eight years ago and he did not have any urological control for last 3 years. However the urinary ultrasound revealed a mass lesion on left kidney and then on axial contrast-enhanced computed tomography (CT) scan, there were two masses on the left kidney. In the magnetic resonance imaging (MRI), the tumor on cortex was depicted as a homogeneous low-signal intensity on the T1-weighted pulse sequence and as a heterogeneous high-signal intensity on the T2-weighted pulse sequence. In pathological evaluation, the biopsy material of the cortical mass was a tumoral lesion containing lipomatous and mixoid areas without atypia, mitosis or necrosis which was diagnosed as myxolipoma. DISCUSSION: Myxolipoma, an uncommon type of lipoma, is a benign tumor composed mainly of fat cells with myxoid (mucus-like) components. In our case, the tumor was composed of mature adipocytes together with areas rich in mucoid substances and there were no malignant features including lipoblasts, mitosis or abundant capillary network. CONCLUSION: Herein we present a case of a fatty tumor originating from the renal capsule with the histologic diagnosis of myxolipoma. To the best of our knowledge, myxolipoma, a very rare form of lipoma, is not reported in kidney, in the literature before.

18.
Int J Surg Case Rep ; 5(12): 902-5, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25460432

RESUMO

INTRODUCTION: Primary epiploic appendagitis (PEA) is self limiting inflammatory disease of colonic epiploic appendices. PRESENTATION OF CASE: Herein, a 40 years old patient describing abdomino-inguinal pain with clotty hematuria having PEA was presented. At first, the patient was thought to have a primary bladder pathology, but after a meticioulus examination, he found to have PEA and managed by conservative measures. DISCUSSION: Although PEA does not require surgical intervention, it may mimic other acute abdominal disorders which can be difficult to differentiate. Appendices overlying the sigmoid colon and cecum are more prone to be affected as they are more elongated and wider in size. The patient is usually admitted due to sudden onset of abdominal pain accompanied with fever, abdominal tenderness and leucocytosis. CONCLUSION: The present case demonstrated that PEA located close to the lower urinary tract especially urinary bladder might present with urinary symptoms such as hematuria. dysuria, pollakuria and inguinal pain.

19.
Int J Clin Exp Med ; 7(5): 1276-83, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24995083

RESUMO

UNLABELLED: Extracorporeal Shock Wave Lithotripsy (SWL) has long been used successfully to dissolve ureteral stones. We researched whether Hounsfield values of ureteral stones is a factor that affects the success of SWL. METHODS: Data from 144 patients who had diagnoses of ureteral stones and underwent SWL, were retrospectively reviewed between January 2011 and December 2012. Urinary tomography of patients was processed and classified into 3 groups by Hounsfield units (Group 1, < 500 HU; Group 2, 500-1000 HU; and Group 3, > 1000 HU) and 2 groups by stone size (Group A; < 1 cm, Group B; > 1 cm). SWL success was analyzed for both of these group types. Failure was defined as any fragments of the stone that remained within the ureter. Results were analyzed by evaluating the predictive factors in both groups. RESULTS: The study included 144 patients (100 men, 44 women) who fit the inclusion criteria. In Hounsfield unit Group 1 (12 women and 44 men), the mean age was 37.2 ± 13.2, stone size was 8.5 ± 2.5 mm, number of shocks was 3240 ± 1414 (1200-7500) and number of treatments was 1.4 ± 0.6. In Group 2 (26 women and 32 men), the mean age was 33.6 ± 7.6, stone size was 9.6 ± 3.1 mm, process number was 3375 ± 2103 (1200-8750) and shock amount was 1.6 ± 0.8. In Group 3 (6 women and 24 men), the mean age was 42.2 ± 13.6, stone size was 11.7 ± 3.0 mm, number of shocks was 4513 ± 2458 (1300-8700) and number of treatments was 2.1 ± 1.2. In size Group 1 (28 women and 74 men), the mean age was 35.8 ± 10.6, stone size was 8.1 ± 1.4 mm, process number was 3105 ± 1604, shock amount was 1.4 ± 0.5 and HU value was 580 ± 297. In Group 2 (16 women and 26 men), the mean age was 39.9 ± 14.2, stone size was 13.9 ± 2.4 mm, number of shocks was 4722 ± 2467, number of treatments was 2.3 ± 1.1 and HU value was 912 ± 270. CONCLUSION: Although stone density predicted the failure of SWL, size of the stone is more important criterion for successful lithotripsy of ureteral stones.

20.
Case Rep Urol ; 2014: 212314, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25013740

RESUMO

Renal stone disease is characterized by the differences depending on the age, gender, and the geographic location of the patients. Seventy-five percent of the renal stone components is the calcium (Ca). The most common type of the stones is the Ca oxalate stones, while Ca phosphate, uric acid, struvite, and sistine stones are more rarely reported. Other than these types, triamterene, adenosine, silica, indinavir, and ephedrine stones are also reported in the literature as case reports. However, to the best of our knowledge, aluminum hydroxide stones was not reported reported before. Herein we will report a 38-years-old woman with the history of recurrent renal colic disease whose renal stone was determined as aluminum hydroxide stone in type. Aluminum mineral may be considered in the formation of kidney stones as it is widely used in the field of healthcare and cosmetics.

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